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To give their glaucoma patients the full benefit of treatment advances, clinicians require clear, actionable insights from knowledgeable subspecialists and researchers. Nitric Oxide in Glaucoma: What Clinicians Need to Know distills and organizes findings about the role of Nitric Oxide (NO) in glaucoma and the role of NO donation in glaucoma therapy in order to make them accessible to ophthalmologists and medical optometrists who want to optimize their decision-making in glaucoma.
Chairperson/Activity Director: James C. Tsai, MD, MBA
CME Reviewer: Matthew J. Gray, MD
CE Reviewer: Tony Cavallerano, OD, FAAO
CHAPTER GUIDE
Introduction
James C. Tsai, MD, MBA
CHAPTER 1: Pathophysiology of Primary Open-angle Glaucoma
Richard K. Lee, MD, PhD
CHAPTER 2: Therapeutic Strategies for Open-angle Glaucoma
Tony Realini, MD, MPH
CHAPTER 3: Nitric Oxide: Historic Perspectives and Recent Developments
Leo Semes, OD, FAAO
CHAPTER 4: Nitric Oxide in Ocular Physiology
W. Daniel Stamer, PhD
CHAPTER 5: Nitric Oxide and Glaucoma
Anne L. Coleman, MD, PhD
Learning Objectives
Review theorized mechanisms of optic nerve damage in glaucoma and recent advances in the understanding of the pathophysiology of glaucomatous optic neuropathy.
Outline aqueous humor dynamics and the control of IOP in healthy and glaucomatous eyes.
Identify sites of action for available IOP-lowering agents and recognize current deficiencies in medical treatment of glaucoma.
Summarize the physiologic function of NO in various bodily systems and identify various NO-donating agents across medicine.
Explain what is known about NO and its function in the eye.
Describe the mechanism of action and therapeutic benefit of enhancing NO signaling in glaucoma patients.